Currently, the funds generated from innovation at the Johns Hopkins School are just a small part of its overall budget. Most of this comes from licensing the Johns Hopkins ACG System, a tool that helps predict health risks and improve patient care. This software was developed by Professor Jonathan Weiner, a leader in health policy.
The School is working to bring more innovation to the forefront with the help of the Innovation Translation Center (ITC). They’re building an entrepreneurial ecosystem. The university is backing initiatives like Johns Hopkins Technology Ventures, which includes the Pava Center and the HEXCITE startup accelerator. The School’s MPH/MBA program is nurturing future startup leaders, and alumni who have launched companies offer valuable mentorship to current students and faculty.
Colleen Cutcliffe, a biotech entrepreneur and representative of the Health Advisory Board, believes that everything needed for success is in place. “All the pieces of the puzzle are there,” she says. However, transforming a research-focused institution into an entrepreneurial hub needs a significant cultural shift.
Phillip A. Sharp, a Nobel Prize-winning biologist and co-founder of Biogen, echoes this sentiment. He emphasizes the need for collaboration beyond the university. “You’ve got to open yourself up to partnerships,” Sharp states, highlighting successful biotech hubs that thrive on connections with engineers and healthcare professionals.
The spirit of collaboration is already part of the School’s culture. Kirk, a faculty member, sees the potential for bringing together clinicians, data experts, and public health specialists to effect real change. Plans are in motion to collaborate with the Hopkins Business of Health Initiative and the Center for Bioengineering Innovation and Design, turning research into practical solutions.
Signs of this cultural shift are emerging. Kirk notes that when he joined the School decades ago, engaging with industry felt taboo. Now, there’s greater acceptance of entrepreneurial efforts. Cutcliffe sees Leung, a well-connected researcher with patents in molecular medicine, as a transformative figure. “He genuinely wants to help others turn ideas into businesses,” she remarks.
In a world increasingly focused on health innovation, this push for entrepreneurship at Johns Hopkins could set a precedent. With a strong foundation in research and emerging partnerships, the School is primed to make significant strides in translating ideas into impactful applications.
For more insights on public health innovation, visit Johns Hopkins ACG and Health Policy and Management.

