Kevin Humphrey was no stranger to pain. As an endurance athlete, he faced long races and tough training. But in January 2024, he felt a nagging back pain that refused to go away. Sleeping became hard, and soon he was coughing. After being treated for pneumonia, he still didn’t feel right. A CT scan revealed an unsettling truth hidden in his left lung.
Despite inconclusive biopsy results, Kevin pressed on for clarity, trusting his instincts that something was wrong. He sought a second opinion at Northwestern Medicine in Chicago in May 2024. There, an unexpected discovery—a tumor pressing on his windpipe—rocked his world. “I couldn’t believe it,” he said, having never smoked or had lung cancer in his family.
Kevin was diagnosed with Stage IV non-small cell adenocarcinoma, a type of lung cancer that increasingly affects young, non-smoking individuals. Experts, like Dr. Jonathan Villena-Vargas, a thoracic surgeon, note a puzzling rise in such cases potentially due to environmental factors. Humphrey’s cancer had already spread, complicating his situation further. The Cleveland Clinic reports a mere 37% five-year survival rate for such advanced stages.
His oncologist, Dr. Daniel Dammrich, explained that while surgery initially wasn’t an option, they discovered a “driver mutation” fueling the cancer. These mutations are often found in younger patients and can alter treatment strategies. This revelation paved the way for targeted immunotherapy combined with chemotherapy.
After beginning this regimen, Kevin faced another challenge. Mid-September brought major surgery to remove half of his left lung. Questions swirled in his mind. Would he still run? Would he ever race again?
Despite the uncertainty, he clung to hope. The Ironman 70.3 race was scheduled for September 15, 2025, just after his surgery. He signed up, determined to train.
Recovery was grueling. Broken ribs and a large incision made even simple tasks tough. But little by little, his strength returned. Training for the Ironman gave him a goal and something to look forward to.
Finally, September 14 arrived. Amid over 1,600 athletes, Kevin raced, finishing in just under five and a half hours. The experience was emotional, filled with memories of his struggles and victories. “Thinking of my boys and family kept me going,” he shared.
Today, Kevin’s health has improved. He had no evidence of disease after treatment, and regular check-ups keep him on track. He even ran the Chicago Marathon just weeks later, finishing more than 40 minutes slower than previous years, but grateful for every step.
Kevin’s story sheds light on the surprising rise of lung cancer in young athletes and the remarkable advancements in treatment options. It also offers a powerful reminder of resilience, the power of support, and the importance of listening to one’s body.
As health trends shift, understanding such cases can help inform future research and raise awareness about unusual cancer diagnoses in non-smokers. For more on lung cancer and treatment options, check out resources from the Cleveland Clinic here and other experts in the field.
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Chicago, Northwestern University, Cancer, Chicago Marathon, Lung Cancer, Ironman, Michigan

