Amgen Expands Oncology Portfolio with Dark Blue Therapeutics Acquisition
Amgen, a biotechnology leader based in Thousand Oaks, California, has made a significant move by acquiring Dark Blue Therapeutics Ltd., a private UK-based company. This deal, valued at up to $840 million, aims to strengthen Amgen’s capabilities in treating acute myeloid leukemia (AML), a challenging and aggressive form of blood cancer.
The acquisition brings an innovative therapeutic approach to Amgen’s portfolio. Dark Blue’s investigational molecule targets and degrades the MLLT1 and MLLT3 proteins, which are known to contribute to AML. Early studies suggest that this method shows promise in fighting leukemia, potentially offering a new direction for treatment amid current options that often lead to resistance.
Dr. Jay Bradner, Amgen’s Executive Vice President, emphasized the urgency for new treatments in AML. “The landscape of leukemia therapies needs innovation. This acquisition will enhance our research into targeted treatments and push forward novel therapies tailored for AML patients,” he said.
The integration of Dark Blue Therapeutics is expected to bolster Amgen’s research on oncology. Amgen has a strong history of developing transformative treatments and currently has an impressive pipeline, addressing various health conditions including cancer and heart diseases.
As of 2024, Amgen has garnered accolades, being named one of the “World’s Most Innovative Companies” and “America’s Best Large Employers” by Forbes. Such recognition underscores its commitment to innovation and excellence in biomedicine.
Recent statistics highlight the pressing need for advancements in leukemia treatment. According to the American Cancer Society, AML is projected to account for over 20,000 new cases in the U.S. alone this year, making this acquisition not just a strategic business move but also a timely response to a growing public health challenge.
Overall, Amgen’s investment in Dark Blue Therapeutics reflects a commitment to improving patient outcomes in oncology, paving the way for new hope in treating resistant forms of cancer.
For more insights on Amgen’s advancements, visit Amgen.com.

