Revolutionizing GI Cancer Treatment: How Personalized Medicine and Technology are Tailoring Care to Your Lifestyle

Personalized medicine is changing how we treat gastrointestinal (GI) cancers. Thanks to advances in next-generation sequencing, doctors can now offer targeted therapies that improve treatment and patient management. Dr. Tiago Biachi, a specialist at Moffitt Cancer Center, emphasizes the importance of these developments.

He also points out that lifestyle choices, like obesity and inactivity, play a significant role in both preventing and managing GI cancers. Interdisciplinary teams are crucial for effective care in this area.

This transcript has been lightly edited for clarity.

Transcript

How has the role of personalized medicine evolved in treating GI cancers?

Personalized medicine, particularly precision oncology, has transformed GI cancer treatment. In the past, many patients received standard treatments. Now, with next-generation sequencing, we can tailor therapies to individual needs. This shift not only improves how we treat patients but also enhances our approach to diagnosis and post-surgery care.

I recently discussed circulating tumor DNA technology at a conference. This new tool is now available in clinics and can be used in various ways, such as screening for colorectal cancer and detecting residual disease after surgery. Our goal is to provide the right treatment at the right time for every patient.

What role does lifestyle and diet play in the prevention and management of GI diseases?

Lifestyle choices are vital in managing GI cancers, perhaps more than in other types of cancer. For instance, obesity and lack of exercise are known risk factors for colorectal cancer. Studies show that patients who are overweight have a higher chance of recurrence compared to those at a healthy weight.

Fatty liver disease, closely linked to lifestyle, is now one of the leading causes of liver cancer. This highlights the need for better preventive measures, especially since obesity is widespread. It’s crucial for both prevention and for those already diagnosed.

How do you see the role of interdisciplinary teams evolving in the treatment and management of GI conditions?

I’ve always loved working in GI cancers because teamwork is essential here. Tumor boards bring together surgeons, radiologists, and other specialists to discuss patient care collaboratively. Each member contributes to finding the best treatment plan.

Patients now have more access to information and often have questions about diet, exercise, and pain management. One provider can’t handle all these aspects alone. It’s vital that we work together to address the overall well-being of the patient, not just their cancer.