A new study from Harvard T.H. Chan School of Public Health and the Department of Veterans Affairs reveals that individuals with type 2 diabetes (T2D) can significantly improve their heart health by combining GLP-1 receptor agonist (GLP-1 RA) medication with healthy lifestyle choices. This research is groundbreaking as it’s the first large-scale examination of how these two factors work together to enhance cardiovascular outcomes.
Frank Hu, an expert in nutrition and epidemiology, emphasizes the study’s key message: even with advanced medications, healthy habits are crucial for managing diabetes and reducing heart disease risk. He states, “Lifestyle habits remain central to diabetes management and can amplify the benefits of modern medications.”
Data from over 98,000 adults with T2D—none had prior cardiovascular issues—was analyzed from the Veterans Affairs’ Million Veteran Program, covering 2011 to 2023. The researchers looked into dietary habits, exercise routines, smoking status, sleep quality, and social support, among other lifestyle factors. They focused on significant cardiovascular events, such as non-fatal strokes and heart attacks.
The findings are striking. Participants using GLP-1 RAs combined with adhering to six to eight healthy habits had a 43% lower risk of major adverse cardiovascular events (MACEs) compared to those not using a GLP-1 RA and following fewer healthy habits. More broadly, individuals who followed all eight recommended habits experienced a 60% lower risk than those who followed one or none.
Hu notes that promoting lifestyle changes is essential, even as new therapies become available. He advocates for public health initiatives that support healthy diets, physical activity, and good stress management.
The study does have limitations, such as the demographic focus primarily on white male veterans, which might affect how broadly the findings apply. However, the results showed consistency across various racial and ethnic groups.
In light of this study, it’s clear that combining medication with a healthy lifestyle can offer significant benefits for heart health in those with T2D. As lifestyle changes and innovative therapies develop, maintaining a balanced approach seems vital for long-term well-being.
For more in-depth details and continued updates, consider checking out the findings published in The Lancet Diabetes & Endocrinology. To learn more, visit the Harvard T.H. Chan School of Public Health and see the full study here.
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Diabetes, Healthy Lifestyle, Agonist, Cardiovascular Disease, Diet, Endocrinology, Heart, Heart Attack, Nutrition, Public Health, Receptor, Research, Sleep, Stress, Stroke, Type 2 Diabetes, Veterans Affairs
