Research from the University of Missouri shows that not moving enough can harm brain health. Led by 81-year-old Frank Booth and his young colleague Nathan Kerr, this study focuses on how inactivity affects us. Booth, a dedicated researcher at Mizzou’s College of Veterinary Medicine, has explored this topic throughout his career.
The study reveals some concerning results. Just 10 days without physical activity can lead to insulin resistance and increased production of harmful substances in the hippocampus. This brain area plays a crucial role in learning and memory. Moreover, muscle disuse during this time raises levels of proteins linked to Alzheimer’s, a serious disease affecting older adults.
These findings back up what many people already believe: staying active is important for brain health. It could help prevent or postpone diseases like Alzheimer’s.
Booth also highlighted a troubling trend. While people are living longer, cases of type 2 diabetes have surged. After age 65, the number of healthy years often decreases. This study aims to help us understand how inactivity affects brain insulin resistance, ultimately guiding us toward a healthier, more enjoyable old age.
Good news: You don’t need to make big changes to see benefits. Research shows that even small amounts of regular exercise can lead to significant health improvements for those who have been inactive.
The study, titled “Hindlimb immobilization induces insulin resistance and elevates mitochondrial ROS production in the hippocampus of female rats,” was published in the Journal of Applied Physiology. It represents a team effort involving Booth, Kerr, Laurel Grisanti, and Scott Rector.
Over his impressive 25-year career, Booth has received nearly $8 million in grants and has published over 170 studies. His work has helped position Mizzou as a top research university, recognized for its high research expenditures over the past decade.
