Unlocking Health Secrets: How Genomic Screening Exposes Hidden Risks for Patients

The Geisinger MyCode Community Health Initiative is offering a fresh look at how genetic testing can change our understanding of health risks. A new evaluation published in JAMA Network Open revealed that among over 175,000 participants, 1 in 30 learned about significant genetic risks that they previously didn’t know about. This is important because more than 90% of those with a genetic risk were unaware of it before participating in the MyCode program.

“Clinical genetic testing often relies on a person’s personal or family history,” says Juliann Savatt, MS, CGC, who co-directs the MyCode program. “This can leave gaps, as some individuals don’t have a family history that prompts testing. Genomic screening can help find those at risk, closing these gaps.”

MyCode has enrolled over 354,000 individuals, examining how genetics impact health. It scans for genetic markers linked to more than 25 health issues, including cancer and heart disease. Identifying these risks can lead to preventive measures or early treatments, which often improve outcomes.

In contrast, many large biobanks do not share genetic findings with participants. This approach can overlook valuable opportunities for better healthcare. As Dr. Christa Martin, chief scientific officer of Geisinger, noted, “MyCode is pioneering in disclosing actionable results. By sequencing 20% of our patient population, we’re one of the largest healthcare initiatives in genomic screening. This transparency supports proactive care, helping identify diseases early and allowing for tailored treatments.”

According to recent surveys, public interest in genetic testing is on the rise, especially among younger generations. A Pew Research Center report found that 59% of adults ages 18–29 are interested in having genetic testing to assess health risks. This growing awareness indicates a shift toward embracing genetic science in personal health management.

Overall, programs like MyCode are changing the landscape of genetic testing. By making genetic information accessible, they empower individuals to take charge of their health in ways that were unimaginable in the past.

For further reading on genomic screening, refer to the original study: Savatt, J. M., et al. (2025). Genomic Screening at a Single Health System. JAMA Network Open. doi.org/10.1001/jamanetworkopen.2025.0917.

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Genomic, Education, Genetic, Genetic Information, Healthcare, Research