Chennai: A New Hope in Cancer Research
The Indian Institute of Technology (IIT) Madras has launched an exciting new resource: the Bharat Cancer Genome Atlas (BCGA). This innovative database focuses on paediatric leukaemia, colorectal, and pancreatic cancers. What makes it groundbreaking? It aims to fill a crucial gap in cancer research by presenting genetic data specifically from Indian patients, who have often been left out of global studies.
This initiative was unveiled on World Cancer Day and is backed by substantial funding from Hyundai Motor India through its ‘Hyundai Hope for Cancer’ program. With ₹56 crore dedicated to this project, it’s a significant boost for cancer research in India.
IIT Madras started the Indian cancer genome program in 2020 with a clear mission: to understand the genomic landscape of different cancers in India. Director Prof. V Kamakoti emphasized that the BCGA will allow for early diagnosis, better tracking of disease progression, and informed treatment choices.
The urgency of this work is highlighted by statistics from the Indian Council of Medical Research, indicating that one in nine Indians will face a cancer diagnosis at some point in their lives. The National Cancer Registry Programme reveals a staggering 12.8% annual increase in cancer cases since 2022, with about 2.5 million people currently affected.
Project Coordinator Prof. S. Mahalingam, head of the Centre of Excellence on Cancer Genomics, stated, “This database will help identify important cancer biomarkers specific to India. It can lead to early detection and the development of tailored treatment strategies.”
Furthermore, the BCGA aims to be a collaborative hub, welcoming data submissions from researchers across various cancer types. This open model could promote a more comprehensive understanding of cancer in the Indian context.
The whole-genome sequencing process involved standardizing protocols for preserving patient samples at extremely low temperatures, a necessary step for accurate analysis. The project has also formed partnerships with organizations like Karkinos Healthcare and the KK Childs Trust Hospital to expand its impact. In addition to research, Hyundai’s partnership includes a ₹3 crore fund to assist low-income families in accessing cancer treatment.
Research shows that focusing on regional genetic variations can lead to breakthroughs in cancer management. As Prof. Kamakoti noted, “India’s unique genetic makeup requires specialized attention in research.”
By bridging the knowledge gap in cancer genomics, the BCGA is poised to have a profound impact on healthcare in India, shaping a future where early detection and effective treatment become a reality for many.
For more information on cancer statistics and ongoing research initiatives, visit ICMR.
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BHARAT CANCER GENOME ATLAS, IIT M CANCER GENOIME DATABASE, IIT-MADRAS UNVEILS BHARAT CANCER GENOME ATLAS TO TACKLE RISING CASES
