Unlocking the Secrets to Healthy Aging: Insights from the World’s Oldest Person

Scientists recently uncovered a fascinating "blueprint" for living a long life by studying Maria Branyas Morera, the world’s oldest person, who passed away last year at 117. Born in 1907 in San Francisco, she spent most of her life in Catalonia, Spain, where she outlived the average life expectancy by over 30 years. Morera attributed her longevity to a mix of "luck and good genetics" and a strong belief in the importance of surrounding herself with positive influences.

Despite healthcare improvements leading to more centenarians, supercentenarians like Morera—those over 110—are still quite rare. A recent study analyzed her DNA and gut health, revealing that her cells functioned as if they were 17 years younger. Researchers looked at her genes, microbiome, and lifestyle, developing a unique platform to compare her health metrics against others in her age group.

One important finding was that Morera’s genome likely contained variations that supported a stronger immune system and offered protection against conditions like cancer and heart disease. This discovery is parallel to research conducted in other "Blue Zones," areas known for high concentrations of centenarians, where factors such as diet and strong social ties significantly contribute to longevity.

An important aspect of the study focused on DNA methylation—how genes express themselves as we age. The researchers found that, while aging typically alters DNA, Morera’s DNA showed a remarkable resistance to these changes, which is unusual for someone her age.

Additionally, Morera’s lipid metabolism stood out: she had low levels of harmful cholesterol and triglycerides associated with heart disease. The study highlighted her gut health, revealing that she had a rich microbiome comprising beneficial bacteria like Bifidobacterium. This bacteria is known for its anti-inflammatory properties, which play a crucial role in overall health.

Morera lived a well-balanced life, avoiding alcohol and smoking, walking daily, and eating a diet rich in fruits, vegetables, and yogurt. Research consistently shows that a Mediterranean diet enhances gut health and overall well-being.

While the link between gut bacteria and longevity is still being explored, the emerging picture indicates that age does not necessarily equate to poor health. Morera’s life and the recent study together suggest that a combination of genetics, lifestyle choices, and environmental factors can play a significant role in not just living longer but living healthily.

For further reading on common lifestyle factors in longevity, you can explore findings from the Blue Zones Project, which studies areas renowned for their high concentration of healthy centenarians.

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