In 79 CE, Mount Vesuvius erupted, causing unimaginable destruction. The volcanic activity buried the cities of Pompeii and Herculaneum, leading to the deaths of thousands. Among the victims was a young man found in bed in the Collegium Augustalium. When scientists unearthed his remains in the 1960s, they discovered something unusual—pieces of dark, glass-like material inside his skull. A recent study has shed light on this phenomenon, revealing that his brain may have turned to glass due to a process called vitrification.

For years, experts debated the nature of the glassy substance in the man’s skull. Some believed it was brain matter, while others disagreed. Many assumed that the hot volcanic flows that covered Herculaneum couldn’t generate enough heat to transform human tissue into glass. However, new research suggests otherwise. A study led by Guido Giordano, a geologist and volcanologist from Roma Tre University, proposes that a superheated ash cloud, reaching temperatures over 510°C (950°F), engulfed the city before the pyroclastic flows arrived. This intense heat likely liquefied the brain, which then cooled rapidly, solidifying it into glass.
The researchers supported their theory by examining charcoal fragments found near the remains. These pieces showed signs of extreme heat followed by quick cooling, similar to conditions seen in other volcanic eruptions. They even drew parallels to recent eruptions like those of Mount Unzen in Japan and the Fuego volcano in Guatemala, which also produced superheated ash clouds.
Using advanced imaging techniques, including electron microscopy, the team analyzed the glassy fragments and found structures that resembled nerve cells. This strongly indicates that the material was indeed brain tissue. “The glass formed from this process allowed for the preservation of biological brain material and its microstructures,” noted forensic anthropologist Pier Paolo Petrone from the Università di Napoli Federico II.
This case marks the first known instance of human brain vitrification in natural circumstances. Scientists know that glass forms under specific conditions—a rapid increase in temperature followed by a swift cooling—that prevents crystallization. Though studies have found vitrified wood at archaeological sites, no human or animal remains have been documented to undergo this transformation until now.
The researchers clarified that the intense heat likely destroyed bones and other soft tissues. However, the skull provided some protection, allowing the brain to remain partially intact during the cooling caused by the ash cloud.
Despite the compelling evidence, some experts remain skeptical. Alexandra Morton-Hayward, a molecular archaeologist from Oxford University, previously questioned whether the glassy material was truly brain tissue. In a paper she co-authored, she suggested that the pyroclastic flows lacked the necessary heat and rapid cooling to permit vitrification and noted the challenge of obtaining samples for independent analysis.
The debate surrounding the “glass brain” is expected to continue as research progresses. With advancements in scientific techniques, future studies may uncover additional examples of this remarkable phenomenon.
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