Thanks to Mary Shelley’s Frankenstein, we have a classic Gothic horror story. Imagine if Dr. Frankenstein were around today—he’d likely face hurdles from an Institutional Review Board (IRB) before even thinking about creating his infamous monster.
While Frankenstein is a work of fiction, real-world history is filled with grotesque examples of unethical research. During World War II, the Nazis committed unspeakable acts on concentration camp victims. In the U.S., unethical studies targeted marginalized groups, such as the infamous Tuskegee Syphilis Study, where Black men were misled and left untreated for syphilis without their knowledge.
These shocking episodes led to the National Research Act in 1974, establishing guidelines for ethical research. This legislation prompted the creation of IRBs to ensure the protection of research subjects, especially those involved in studies that use federal funding.
At the University of Guam (UOG), the IRB is responsible for reviewing research proposals concerning human subjects. There’s also an Institutional Animal Care and Use Committee for animal studies. Before any research begins, investigators must submit an application detailing their methods, participant questions, and ethical considerations.
In 2025, the UOG IRB reviewed 181 applications, reflecting diverse topics. Studies included the impact of social media on CHamoru youth and strategies for managing stress among CHamoru farmers. According to the UOG Office of Research and Sponsored Programs, adherence to rigorous ethical guidelines nurtures trust and integrity in research.
Peter Barcinas, the IRB chair, explained, “Applications are carefully reviewed and approved only when all concerns are addressed.” This year, UOG researchers have shown that ethics in research is not just about following rules; it’s crucial for the health and culture of the community.
At the recent 2026 Economic Forum in Guam, Melanie Mendiola of BG Investment Services noted that over $61 million has been invested in STEM research at UOG since 2019. This investment not only boosts the economy but also strengthens community health and environmental practices.
In our rapidly changing world, the lessons from past research ethics remain vital. By ensuring that the rights and well-being of participants are prioritized, we pave the way for ethical advancements that respect both people and the planet.
For more details on research at UOG, you can check their Office of Research and Sponsored Programs and learn more about the UOG IRB.
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