Researchers at the University of Nottingham have discovered that patients with neurological and mental health disorders prefer non-invasive treatments over traditional pharmaceuticals. The study highlights the growing interest in neuromodulation, a technique that alters brain activity using targeted stimulation, whether electrical or chemical.
In their study, published in Scientific Reports, nearly 800 participants shared their views on various neuromodulation therapies. The results showed that many people favor these new methods over existing treatments. Dr. Marcus Kaiser, who led the research, emphasized the importance of educating patients about these options. Properly informing them can shape their perceptions and improve their willingness to engage with new treatments.
The World Health Organization estimates that 322 million people worldwide suffer from depression, while 264 million struggle with anxiety. With these numbers rising, it’s crucial to develop effective treatments that can enhance the lives of patients and their families.
Many patients often feel trapped by medications, with about 50% of those with major depressive disorders not sticking to their prescribed treatment. This situation has sparked a growing interest in non-invasive neuromodulation techniques, like Transcranial Magnetic Stimulation, which have shown promise in treating depression safely. However, how do potential new methods, such as focused ultrasound stimulation, resonate with the public?
Dr. Cyril Atkinson-Clement, part of the study team, asked participants for their opinions on neuromodulation both before and after they received detailed information about different treatment technologies. Participants learned about the pros and cons of various methods, including drugs, implants, ultrasound, magnets, and electrical stimulations. They were then asked to rank their preferences.
The results revealed that ultrasound stimulation was the most favored option, seen as both safe and effective. Pharmaceutical drugs were viewed as a middle ground, as many people expressed concerns about their side effects and long-term effectiveness.
One participant shared, “We need to move away from the cycle of using more drugs to counteract side effects.”
Initially, 81% of participants showed interest in neuromodulation, with 48% feeling confused about it. After receiving more information, optimism jumped to 70%, and excitement increased to 62%, although some confusion still lingered.
Another participant noted, “The potential for treatments with fewer side effects and longer-lasting effects than current drugs is promising.”
Dr. Kaiser pointed out that the findings highlight the public’s preference for non-invasive treatments. This presents an opportunity for government and industry leaders to focus on developing and promoting safe brain stimulation techniques.
Overall, the study underscores the need for more innovative and less invasive treatment options in mental health and neurological care, providing hope for countless patients seeking relief from their conditions.
Source: Atkinson-Clement, C., et al. (2025). Neuromodulation perception by the general public. Scientific Reports. doi.org/10.1038/s41598-025-89437-8.
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Source linkMental Health, Alzheimer's Disease, Anxiety, Brain, Depression, Drugs, Medicine, Nerve, Nerve activity, Neuromodulation, Research, Schizophrenia, Ultrasound
