Groundbreaking FDA Approval: Meet the First CRISPR-Edited Pigs for Sustainable Food Innovation!

Ever thought about gene-edited bacon? This week, the FDA gave the green light to gene-edited pigs by PIC, a company focused on livestock genetics. This approval allows the use of a specific gene edit in pigs raised for food.

PIC used CRISPR, a cutting-edge gene-editing tool, to create pigs that can resist a major viral infection known as porcine reproductive and respiratory syndrome (PRRS). This virus can damage the swine industry significantly. While it may take a while for these gene-edited pigs to reach our plates, their potential is huge.

Matt Culbertson, PIC’s COO, shared, “Years of research went into this. We collaborated with the FDA to ensure safety and efficacy.” The gene edit targets a receptor that PRRS uses to infect pig cells, making the pigs nearly immune to the virus.

PRRS first emerged a few decades ago, causing havoc among pig farms. It leads to the deaths of young pigs and reproductive issues in breeding sows. The World Organization for Animal Health reports that PRRS costs the U.S. pork industry about $560 million each year. This makes genetic solutions like those from PIC crucial for producers.

The process of creating these pigs starts with editing early embryos. These edited embryos are implanted in gilts, which are young female pigs. This ensures that the beneficial trait is passed down through generations. Remarkably, these pigs should taste just like their unmodified counterparts, making them appealing to consumers.

PIC isn’t the first to receive FDA approval for gene-edited livestock. In 2020, the FDA approved Galsafe pigs from Revivicor, designed to eliminate a sugar that can cause allergies in humans. The FDA has also approved genetically modified salmon, yet acceptance in the commercial market has been tricky for many companies.

Despite potential roadblocks, PIC’s straightforward approach could make their pigs a game-changer in the market. If successful, we may see a rise in genetically engineered meats that are safer and more resilient to diseases.

For the pigs to be commercially available in the U.S., PIC will need to navigate approvals in other key markets like Canada, Mexico, and China. However, they anticipate that these pigs will not be ready for purchase until 2026 at the earliest.

As gene editing gains traction, many consumers are curious. A recent survey found that 64% of people are open to trying gene-edited foods if they are proven safe. Though there’s still some hesitation, the combination of taste, safety, and health benefits might persuade more people to embrace this innovation.

For more insights on the implications of gene editing in agriculture, check out the FDA’s announcement.

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agriculture,CRISPR,gene editing,infectious diseases