Revolutionizing Technology: Scientists Develop ‘Living’ Computers Powered by Human Cells

In a fascinating blend of biology and technology, researchers are developing computers made from living cells. This area of innovation is called biocomputing, and it’s unlocking exciting possibilities.

In Switzerland, Dr. Fred Jordan and his team at FinalSpark are at the forefront of this work. They envision data centers filled with “living” servers that could learn much like AI, using significantly less energy. Instead of using traditional hardware and software, they’re creating “wetware”—a term that reflects the biological foundation of their technology.

The process begins with stem cells derived from human skin. These stem cells are turned into clusters known as organoids, which can then be connected to electrodes. By sending electrical signals to these organoids, researchers can explore their responses, much like testing a computer.

Dr. Jordan admits that the idea of using neurons as tiny machines can seem strange. “In science fiction, these concepts have been around for a while,” he explains. Yet this approach challenges how we think about our own brains and technology.

In the lab, small, white spheres contain these organoids. Though they’re not as complex as a human brain, they have similar building blocks. After growing for months, these organoids can respond to simple commands, showing measurable electrical activity. This interactivity is the first step toward getting the organoids to learn and adapt over time.

However, keeping these living computers alive presents challenges. Organoids lack blood vessels, which makes sustaining them difficult. Simon Schultz, a neurotechnology expert at Imperial College London, highlights that while organoids may last up to four months, scientists still don’t fully understand how to keep them functioning long-term. Interestingly, just before organoids die, there can be a surge of electrical activity, similar to what some humans experience at the end of life.

FinalSpark is not alone in this innovative field. In Australia, Cortical Labs recently made headlines by getting artificial neurons to play the classic game Pong. Meanwhile, Johns Hopkins University in the U.S. is using mini-brains to develop treatments for neurological disorders.

Dr. Lena Smirnova, leading research at Johns Hopkins, believes biocomputing is exciting but still in the early stages. She asserts it will likely complement, rather than replace, traditional silicon-based computers.

As science fiction blurs with reality, Dr. Jordan reflects on his journey: “I’ve always been a fan of science fiction. Now I feel like I’m in the book, writing the book.”

In a rapidly changing tech landscape, biocomputing shows remarkable promise. By continuing to explore this intersection of biology and technology, scientists aim to create machines that not only perform tasks but also evolve in their capabilities.

To learn more about these advancements, check sources like the Johns Hopkins University research and Cortical Labs.

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