Week 2 NFL Predictions: Expert Picks & Score Forecasts for Must-See Primetime Matchups

Week 1 of the 2025 NFL season didn’t disappoint. There were thrilling moments, dramatic finishes, and a few surprises that left fans buzzing. Now, as we look ahead to Week 2, excitement continues to build.

This week promises plenty of entertaining matchups. Notably, the primetime games feature at least one playoff team from last season and several star quarterbacks. Every game has the potential for drama and standout performances.

In case you missed it, we’ve already made predictions for all the games. Here’s a closer look at the key primetime matchups:

Washington Commanders (1-0) vs. Green Bay Packers (1-0)

Thursday, September 11, 8:15 PM ET

Week 2 kicks off with an exciting game as the Green Bay Packers host the Washington Commanders. Both teams impressed in their opening week. The Packers had a particularly striking victory, dominating a Lions team that had a strong season last year.

This game will likely hinge on the performance of each quarterback. The Packers bolstered their roster by trading for star linebacker Micah Parsons. This move boosted team morale and showed that they are aiming for a championship run this season.

Traveling for an away game isn’t easy, especially for a strong team like the Commanders. This matchup could truly be a back-and-forth affair. However, I’m betting on the Packers to edge it out with a final score prediction of 27-24.

Atlanta Falcons (0-1) vs. Minnesota Vikings (1-0)

Sunday, September 14, 8:20 PM ET

After a rocky start, the Vikings made a comeback against the Bears, largely thanks to quarterback JJ McCarthy’s three touchdown throws in the fourth quarter. His performance even earned him NFC Player of the Week honors, despite a couple of missteps earlier in the game.

On the other side, Michael Penix Jr. of the Falcons nearly led his team to victory against the Bucs. Unfortunately, the defense struggled to seal the deal. This inconsistency might pose a challenge for the Falcons moving forward.

With the Vikings riding high from their previous game and set to play at home in front of a supportive crowd, they have the momentum. Based on both teams’ performances, I predict the Vikings will win this match 23-19.

These two matchups set the stage for an entertaining week in the NFL. Fans can expect plenty of surprises and intense action.

For more insights and detailed analysis on NFL games, check out sources like ESPN and NFL.com.

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